Dmel\tobi - FlyBase Gene Report

FlyBase: a database for drosophila genetics and molecular biology. ... Dmel\tobi. Species. D. melanogaster. Name. target of brain insulin. Annotation Symbol. Chemicaldataclass(FBch)inFlyBase ProteinandRNAstructuresaddedtoGeneReports FlyBoardelectionresults UpdatetoorthologycallsfromOrthoDB GORibbonStacksinGeneGroupreports Previous Next FB2022_02,releasedMarch29,2022 Gene:Dmel\tobi FB2022_02,releasedMarch29,2022 Gene:Dmel\tobi Menu Home Tools ToolsOverview&Help Query by symbols/IDs BatchDownload SequenceDownloader Upload/ValidateIDs FeatureMapper Search/Browse Portals QuickSearch Vocabularies QueryBuilder CytoSearch InteractionsBrowser ImageBrowse GenomicsTools BLAST GBrowse JBrowse CytoSearch FeatureMapper ChromosomeMaps CoordinatesConverter SequenceDownloader RNA-SeqSearch Overview RNA-SeqSimilarity RNA-SeqProfile RNA-SeqByRegion GBrowse JBrowse Submit Data Fast-TrackYourPaper SubmitPersonalCommunication FeedbackonGeneSnapshots Downloads Overview CurrentRelease ArchivedReleases MapConversion FTPSite: Releases(FTP) Genomes(FTP) Links ExternalResources ModelOrganisms(MODs) AllianceofGenomeResources BeeBase DictyBase EcoCyc Gramene MGI PomBase Pseudobase RGD SGD TAIR VectorBase WormBase Xenbase ZFIN StockCollections BloomingtonDrosophilaStockCenter(BDSC) Exelixis FlyORF KoreaDrosophilaResourceCenter(KDRC) KyotoStockCenter NIG-FLY TsinghuaFlyCenter(THFC) ViennaDrosophilaResourceCenter(VDRC) Funding BDGP DGRC DRSC/TRiP DISbyissue FlyBook FlyExpress InteractiveFly modENCODE TextpressoforFly Community FlyBase Community Fast-TrackYourPaper FlyBase Community Advisory Group Recent Papers With Technical Advances GeneSnapshots FlyBaseForum Newsletter FlySlackCommunity Twitter Species Phylogeny SequencedSpecies SyntenyTable ColorIllustrations About Release Notes NewInThisRelease ReleaseSchedule FlyBasePositions CitingFlyBase FlyBaseCopyright FlyBaseConsortium FlyBase Publications FlyBasePresentations FlyBaseSupport Help VideoTutorials Toolhelp Reporthelp InfoforAuthors Authorguidelines CitingFlyBase Fast-TrackYourPaper GeneSnapshots Personal communications Linkingto/fromFlyBase Nomenclature Curationdocumentation ControlledVocabulariesinFlyBase GeneModelAnnotation GeneOntology(GO)Annotation Nontraditionalalleles Vectors&Constructs NewtoFlies HelpIndex FlyBaseForDevelopers ContactFlyBase Archives PriorRelease OtherArchives     JumptoGene SearchFlyBase Go Open Close GeneralInformation Symbol Dmel\tobi Species D.melanogaster Name targetofbraininsulin AnnotationSymbol CG11909 FeatureType protein_coding_gene FlyBaseID FBgn0261575 GeneModelStatus Current StockAvailability 3publiclyavailable GeneSummary (Alliance, FBgn0261575 ) (FlyBaseAutomaticallyGeneratedSummary) ContributeaGeneSnapshotforthisgene. AllSummaries AllianceAutosummaryGeneGroupInteractiveFly KeyLinks GenomicLocation Cytogeneticmap 96D2-96D2 Sequencelocation 3R:25,344,761..25,346,921[-] Recombinationmap (fulldetails) 3-87 RefSeqlocus NT_033777REGION:25344761..25346921 Sequence GeneregionExtendedGeneregionCDSIntronsExonsTranscriptsTranslations5'UTR3'UTRGetSequenceGetDecoratedFASTA GenomicMaps JBrowseGBrowseHelpmechoose OtherGenomeViews ThefollowingexternalsitesmayusedifferentassembliesorannotationsthanFlyBase. NCBI UCSC Ensembl PopFly Function GOSummaryRibbons GeneOntology(GO)Annotations(2terms) MolecularFunction(1term) TermsBasedonExperimentalEvidence(0terms) TermsBasedonPredictionsorAssertions(1term) CVTerm Evidence References enableshydrolaseactivity,hydrolyzingO-glycosylcompoundsinferredfromelectronicannotationwithInterPro:IPR000322 (assignedby InterPro ) (FlyBaseCuratorsetal.,2004-)BiologicalProcess(1term) TermsBasedonExperimentalEvidence(0terms) TermsBasedonPredictionsorAssertions(1term) CVTerm Evidence References involved_incarbohydratemetabolicprocessinferredfromelectronicannotationwithInterPro:IPR000322 (assignedby InterPro ) (FlyBaseCuratorsetal.,2004-)CellularComponent(0terms) TermsBasedonExperimentalEvidence(0terms) TermsBasedonPredictionsorAssertions(0terms) GeneGroup(FlyBase) OTHERO-GLYCOSYLHYDROLASES ProteinFamily(UniProt) - ProteinSignatures(InterPro) Glycosidehydrolasefamily31 Glycosidehydrolasesuperfamily Glycosylhydrolase,all-beta Summaries AutomatedDescription(AllianceofGenomeResources) (Alliance, FBgn0261575 ) AutomaticallyGeneratedSummary(FlyBase)GeneGroup(FlyBase)OTHERO-GLYCOSYLHYDROLASES - OtherO-glycosylhydrolasesgroupisacollectionofO-glycosylhydrolasesthatdonotfitintoanyoftheothermajorO-glycosylhydrolasegroups.GeneModelandProducts NumberofTranscripts 1 NumberofUniquePolypeptides 1 Pleaseseethe JBrowseviewof Dmel\tobi forinformationonotherfeatures TosubmitacorrectiontoagenemodelpleaseusetheContactFlyBaseform ProteinDomains(viaPfam) Isoformdisplayed:PfamproteindomainsInterPronameclassificationstartend ProteinDomains(viaSMART) Isoformdisplayed:SMARTproteindomainsInterPronameclassificationstartend StructureNewSection Protein3Dstructure (PredictedbyAlphaFold)  (AlphaFoldentryQ9VBR6) Ifyoudon'tseetheviewertotheright,refreshyourbrowser. ModelConfidence: Veryhigh(pLDDT>90) Confident(90>pLDDT>70) Low(70>pLDDT>50) Verylow(pLDDT<50) AlphaFoldproducesaper-residueconfidencescore(pLDDT)between0and100. SomeregionswithlowpLDDTmaybeunstructuredinisolation. CommentsonGeneModel Genemodelreviewedduring5.43 Genemodelreviewedduring5.48 SequenceOntology:ClassofGene gene(BuchandPankratz,2007)nuclear_geneprotein_coding_geneTranscriptData AnnotatedTranscripts Name FlyBaseID RefSeqID Length(nt) Assoc.CDS(aa)tobi-RAFBtr0084847NM_1431342104657AdditionalTranscriptDataandCommentsReportedsize(kB)CommentsExternalDataCrossreferencesPolypeptideData AnnotatedPolypeptides Name FlyBaseID PredictedMW(kDa) Length(aa) TheoreticalpI RefSeqID GenBank tobi-PAFBpp008422174.66574.63NP_651391AAF56462PolypeptideswithIdenticalSequences Thereisonlyoneproteincodingtranscriptandonepolypeptideassociatedwiththisgene AdditionalPolypeptideDataandCommentsReportedsize(kDa)CommentsExternalDataCrossreferencesInterPro - Adatabaseofproteinfamilies,domainsandfunctionalsitesGlycosidehydrolasefamily31 Glycosylhydrolase,all-beta Glycosidehydrolasesuperfamily LinkoutsSequencesConsistentwiththeGeneModel Nucleotide/PolypeptideRecords AE014297 / AAF56462AI296800BI580695BT023924EV576616EV592901EV593287GH743242GH747299 UniProtQ9VBR6 MappedFeatures Clicktogetalistofregulatoryfeatures(enhancers,TFBS,etc.)andgenedisruptions(pointmutations,indels,etc.)withinoroverlapping Dmel\tobi usingtheFeatureMappertool. FeatureMapperExternalData CrossreferencesEukaryoticPromoterDatabase - Acollectionofdatabasesofexperimentallyvalidatedpromotersforselectedmodelorganisms.tobi_1 LinkoutsExpressionData ExpressionSummaryRibbons ColoredtilesinribbonindicatethatexpressiondatahasbeencuratedbyFlyBase forthatanatomicallocation. Colorlesstilesindicatethatthereisnocurateddataforthatlocation. Forcompletestage-specificexpressiondata,viewthe modENCODEDevelopmentRNA-SeqsectionunderHigh-ThroughputExpressionbelow. TranscriptExpression insituStageTissue/Position(includingsubcellularlocalization)Referenceadultstageadultgut|restricted(Buchetal.,2008)fatcell(Buchetal.,2008) AdditionalDescriptiveData Markerfor   SubcellularLocalization CVTerm PolypeptideExpression massspectroscopyStageTissue/Position(includingsubcellularlocalization)Referenceadultstageadulthead • membrane(Aradskaetal.,2015) AdditionalDescriptiveData Markerfor   SubcellularLocalization CVTermEvidenceReferencesExpressionDeducedfromReporters High-ThroughputExpressionData AssociatedToolsGBrowse-VisualdisplayofRNA-Seqsignals ViewDmel\tobiinGBrowse2 RNA-SeqbyRegion-SearchRNA-Seqexpressionlevelsbyexonorgenomicregion ViewexonicexpressionbydevelopmentalstageforDmel\tobi ViewexonicexpressionbytissueforDmel\tobiBulkDownloads RNA-SeqRPKMvaluesforallgenesReference SeeGelbartandEmmert,2013 foranalysisdetailsanddatafilesforallgenes. DevelopmentalProteome:LifeCycle DevelopmentalProteome:Embryogenesis tobiExternalDataandImages LinkoutsBDGPexpressiondata - PatternsofgeneexpressioninDrosophilaembryogenesisFBgn0261575 DRscDB - Asingle-cellRNA-seqresourcefordatamininganddatacomparisonacrossspecies43072/tissue=All EMBL-EBISingleCellExpressionAtlas - SinglecellexpressionacrossspeciesFBgn0261575 FlyAtlas - Adultexpressionbytissue,usingAffymetrixDros2arrayFBgn0039330 FlyAtlas2 - ADrosophilamelanogasterexpressionatlaswithRNA-Seq,miRNA-Seqandsex-specificdataFBgn0261575 Fly-FISH - AdatabaseofDrosophilaembryoandlarvaemRNAlocalizationpatternsCG11909 ImagesFlyBaseWiki ImageBasedResources Alleles,Insertions,TransgenicConstructs,andAberrations ClassicalandInsertionAlleles (0) ForAllClassicalandInsertionAllelesShowPre-selecteddataChoosespecificdata   Otherrelevantinsertions TransgenicConstructs (8) ForAllAllelesCarriedonTransgenicConstructsShowPre-selecteddataChoosespecificdata Transgenicconstructscontaining/affectingcodingregionoftobi TransgenicconstructscontainingregulatoryregionoftobiAberrations(DeficienciesandDuplications) (1) Inferredfromexperimentation (1) GenedisruptedinDf(3R)Exel6202(Ryder,2004.4.26) Inferredfromlocation (0) ExporttoHitList  Df(3R)BSC522 Df(3R)BSC849 Df(3R)Exel6202 Dp(3;2)GV-CH321-96O04 AllelesRepresentingDisease-ImplicatedVariants Phenotypes Formoredetailsaboutaspecificphenotypeclickontherelevantallelesymbol. LethalityAllelelethal,withScer\GAL41032.hxtobiUAS.cBalethal,withScer\GAL4αTub84B.PLtobiUAS.cBalethal-alldieduringembryonicstage,withScer\GAL4Act.PUtobiUAS.cBaviable,withScer\GAL41032.hxtobidsRNA.2A2.UASviable,withScer\GAL41032.hx,tobi1B5.Sym.UAStobia.1B5.Sym.UASviable,withScer\GAL41032.hx,tobia.1B5.Sym.UAStobi1B5.Sym.UASviable,withScer\GAL4Act.PUtobidsRNA.2A2.UASviable,withScer\GAL4Act.PU,tobi1B5.Sym.UAStobia.1B5.Sym.UASviable,withScer\GAL4Act.PU,tobia.1B5.Sym.UAStobi1B5.Sym.UASviable,withScer\GAL4fkh.XB30tobiUAS.cBaviable,withScer\GAL4Mef2.PRtobiGD6263viable,withScer\GAL4pnr-MD237tobiGD6263viable,withScer\GAL4ppl.PPtobidsRNA.2A2.UAStobiUAS.cBaviable,withScer\GAL4ppl.PP,tobi1B5.Sym.UAStobia.1B5.Sym.UASviable,withScer\GAL4ppl.PP,tobia.1B5.Sym.UAStobi1B5.Sym.UASviable,withScer\GAL4tin.CΔ4tobiGD6263OtherPhenotypesAlleledecreasedbodysize|heatsensitive,withScer\GAL4hs.2sevtobiUAS.cBashortlived,withScer\GAL4fkh.XB30tobiUAS.cBasomedieduringembryonicstage,withScer\GAL4Act.PUtobiUAS.cBaPhenotypemanifestinAlleleOrthologs Downloads DownloadAllDIOPTOrthologsHumanOrthologs(viaDIOPTv8.0) Homosapiens(Human)(7) Species\GeneSymbol Score BestScore BestReverseScore SourceComparaeggNOGHieranoidHomologeneInparanoidIsobaseOMAOrthoDBOrthoFinderOrthoInspectororthoMCLPantherPhylomeRoundUpTreeFamZFINAlignmentComplementation?Transgene?Hsap\MYORG14of15YesYes Hsap\GAA2of15NoYes Hsap\GANC2of15NoNo Hsap\MGAM2of15NoYes Hsap\SI2of15NoYes Hsap\GANAB1of15NoNo Hsap\MGAM21of15NoYes ModelOrganismOrthologs(viaDIOPTv8.0) Musmusculus(laboratorymouse)(6) Species\GeneSymbol Score BestScore BestReverseScore SourceComparaeggNOGHieranoidHomologeneInparanoidIsobaseOMAOrthoDBOrthoFinderOrthoInspectororthoMCLPantherPhylomeRoundUpTreeFamZFINAlignmentComplementation?Transgene?Mmus\Myorg12of15YesYes Mmus\Gaa2of15NoYes Mmus\Ganc2of15NoNo Mmus\Mgam2of15NoYes Mmus\Sis2of15NoYes Mmus\Ganab1of15NoNo Rattusnorvegicus(Norwayrat)(5) Rnor\Myorg12of13YesYes Rnor\Gaa2of13NoYes Rnor\Ganc2of13NoNo Rnor\Si2of13NoYes Rnor\Ganab1of13NoNo Xenopustropicalis(Westernclawedfrog)(6) Xtro\myorg9of12YesYes Xtro\gaa2of12NoYes Xtro\ganc2of12NoNo Xtro\ganab1of12NoNo Xtro\LOC1004943581of12NoYes Xtro\mgam1of12NoYes Daniorerio(Zebrafish)(8) Drer\myorg9of15YesYes Drer\si:ch211-117c19.19of15YesYes Drer\si:ch211-236l14.44of15NoYes Drer\gaa2of15NoYes Drer\ganc2of15NoNo Drer\ganab1of15NoNo Drer\si:ch73-12o23.11of15NoYes Drer\zgc:1719671of15NoNo Caenorhabditiselegans(Nematode,roundworm)(3) Cele\aagr-21of15YesYes Cele\aagr-31of15YesNo Cele\D2096.121of15YesYes Arabidopsisthaliana(thale-cress)(0) Norecordsfound.Saccharomycescerevisiae(Brewer'syeast)(1) Scer\ROT21of15YesNo Schizosaccharomycespombe(Fissionyeast)(0) Norecordsfound.OtherOrganismOrthologs(viaOrthoDB) Paralogs Downloads DownloadAllDIOPTParalogs Paralogs(viaDIOPTv8.0) Drosophilamelanogaster(Fruitfly)(2) GeneSymbol ScoreSourceComparaeggNOGHomologeneInparanoidIsobaseOrthoDBOrthoFinderorthoMCLPantherRoundUpAlignmentCG330805of10 GCS2α2of10 HumanDiseaseAssociations FlyBaseHumanDiseaseModelReportsinsulinpathwayeffects,MYORG-related DiseaseModelSummaryRibbonDiseaseOntology(DO)AnnotationsModelsBasedonExperimentalEvidence (0) Allele Disease Evidence References PotentialModelsBasedonOrthology (0) HumanOrtholog Disease Evidence References ModifiersBasedonExperimentalEvidence (0) Allele Disease Interaction References DiseaseAssociationsofHumanOrthologs(viaDIOPTv8.0andOMIM) Notethatorthologcallssupportedbyonly1or2algorithms(DIOPTscore<3)arenotshown.Homosapiens(Human)GenenameScoreOMIMOMIMPhenotypeDOtermComplementation?Transgene?MYORG;myogenesisregulatingglycosidase(putative)14of15618255BASALGANGLIACALCIFICATION,IDIOPATHIC,7,AUTOSOMALRECESSIVE;IBGC7 FunctionalComplementationData FunctionalcomplementationdataiscomputedbyFlyBaseusingacombinationoftheorthologydata obtainedfromDIOPTandOrthoDBandtheallele-levelgeneticinteractiondatacuratedfromthe literature. Interactions SummaryofPhysicalInteractions esyNNetworkDiagram Showneighbor-neighborinteractions:OffOnSelectLayout:ForceDirectedCircleConcentricLegend:ProteinRNASelectedInteractor(s) InteractionsBrowser ViewinInteractionsBrowserPleaseseethePhysicalInteractionreportsbelowforfulldetailsprotein-proteinPhysicalInteractionAssayReferencestobi-CG4325experimentalknowledgebased(Guruharshaetal.,2011)tobi-Calrexperimentalknowledgebased(Guruharshaetal.,2011)tobi-ERp60experimentalknowledgebased(Guruharshaetal.,2011)tobi-I-2experimentalknowledgebased(Guruharshaetal.,2011)tobi-Pcdexperimentalknowledgebased(Guruharshaetal.,2011)tobi-cluexperimentalknowledgebased(Guruharshaetal.,2011)tobi-tsrexperimentalknowledgebased(Guruharshaetal.,2011)SummaryofGeneticInteractions esyNNetworkDiagram Startinggene(s)InteractiontypeInteractinggene(s)ReferenceStartinggene(s)InteractiontypeInteractinggene(s)ReferenceExternalData LinkoutsDroID - Acomprehensivedatabaseofgeneandproteininteractions.FBgn0261575 MIST(protein-protein) - AnintegratedMolecularInteractionDatabasetobi Pathways SignalingPathways(FlyBase) MetabolicPathways ExternalData LinkoutsKEGGPathways - Wiringdiagramsofmolecularinteractions,reactionsandrelations.Galactosemetabolism Starchandsucrosemetabolism Metabolicpathways GenomicLocationandDetailedMappingData Chromosome(arm)3RRecombinationmap3-87Cytogeneticmap96D2-96D2Sequencelocation3R:25,344,761..25,346,921[-] FlyBaseComputedCytologicalLocation Cytogeneticmap Evidenceforlocation 96D2-96D2LimitscomputationallydeterminedfromgenomesequencebetweenP{PZ}Aats-gln05461andP{EP}EP3354 ExperimentallyDeterminedCytologicalLocation Cytogeneticmap Notes References ExperimentallyDeterminedRecombinationData Location3-87(FlyBase,2016) 3-85.9(Comeronetal.,2012) Leftof(cM)Rightof(cM)NotesStocksandReagents Stocks(3) Aberrationsincludingdeletionsofthisgene Aberrationsincludingduplicationsofthisgene Bloomington53379y1v1;P{TRiP.HMJ02101}attP40VDRCv103544P{KK100897}VIE-260Bv14734w1118;P{GD6263}v14734GenomicClones (12)  BACR10P10 CH321-13D2 CH321-18E12 CH321-22N11 CH321-71K7 CH321-96O4 CH322-18P24 CH322-28C23 CH322-100M9 CH322-118B11 CH322-141E1 CH322-188A17 ListGenBankIDsPleaseNoteFlyBaseno longercuratesgenomiccloneaccessionssothislist maynotbecomplete cDNAClones (8)  ListGenBankIDsClonesConsistentwithTranscriptsPleaseNote ThissectionlistscDNAsandESTsthatfallwithinthegenomicextent ofthegenemodel,whichmayincludecDNAsandESTs ofgeneswithinintrons,orof overlapping genes.Pleasesee GBrowse foralignmentofthecDNAsandESTstothegenemodel. cDNAclones,fullysequencedBDGPDGCclonesRE74917 OtherclonesDPiM_RE74917 DrosophilaGenomicsResourceCentercDNAclones ForeachfullysequencedcDNAtheDGRCmaintainsvariousformsofthecDNA(e.gtaggedoruntagged) inseveraldifferenthostvectorsforsubsequentcloningandexpressioninDrosophilaand Drosophilacelllines. FBgn0261575 cDNAClones,EndSequenced(ESTs)BDGPDGCclonesLP10881 OtherclonesDmel_dig_010288_0643_0519 Dmel_neb_014538_0695_3023 Dmel_neb_015020_0700_2507 RP001007478 RP001052710 RNAiandArrayInformation LinkoutsDRSC - ResultsfrmRNAiscreensFBgn0261575 GenomeRNAi - Adatabaseforcell-basedandinvivoRNAiphenotypesandreagents43072 AntibodyInformation LaboratoryGeneratedAntibodies   CommerciallyAvailableAntibodies  OtherInformation RelationshiptoOtherGenes Sourcefordatabaseidentifyof Sourcefordatabasemergeof Sourceformergeof:tobiCG11909(Buchetal.,2008) Additionalcomments OtherComments OriginandEtymology Discoverer Etymology Identification ExternalCrossreferencesandLinkouts(31)SequenceCrossreferencesNCBIGene - Geneintegratesinformationfromawiderangeofspecies.Arecordmayincludenomenclature,ReferenceSequences(RefSeqs),maps,pathways,variations,phenotypes,andlinkstogenome-,phenotype-,andlocus-specificresourcesworldwide.43072 GenBankNucleotide - Acollectionofsequencesfromseveralsources,includingGenBank,RefSeq,TPA,andPDB.BI580695 GenBankProtein - Acollectionofsequencesfromseveralsources,includingtranslationsfromannotatedcodingregionsinGenBank,RefSeqandTPA,aswellasrecordsfromSwissProt,PIR,PRF,andPDB.AAF56462 RefSeq - Acomprehensive,integrated,non-redundant,well-annotatedsetofreferencesequencesincludinggenomic,transcript,andprotein.NM_143134 NP_651391 UniProt/GCRP - Thegene-centricreferenceproteome(GCRP)providesa1:1mappingbetweengenesandUniProtaccessionsinwhichasingle'canonical'isoformrepresentstheproduct(s)ofeachprotein-codinggene.Q9VBR6 UniProt/TrEMBL - AutomaticallyannotatedandunreviewedrecordsofproteinsequenceandfunctionalinformationQ9VBR6 OthercrossreferencesAlphaFoldDB - AlphaFoldprovidesopenaccesstoproteinstructurepredictionsforthehumanproteomeandotherkeyproteinsofinterest,toacceleratescientificresearch.Q9VBR6 BDGPexpressiondata - PatternsofgeneexpressioninDrosophilaembryogenesisFBgn0261575 DrosophilaGenomicsResourceCenter - DrosophilaGenomicsResourceCenter(DGRC)cDNAclonesFBgn0261575 DRscDB - Asingle-cellRNA-seqresourcefordatamininganddatacomparisonacrossspecies43072/tissue=All EMBL-EBISingleCellExpressionAtlas - SinglecellexpressionacrossspeciesFBgn0261575 EukaryoticPromoterDatabase - Acollectionofdatabasesofexperimentallyvalidatedpromotersforselectedmodelorganisms.tobi_1 FlyAtlas - Adultexpressionbytissue,usingAffymetrixDros2arrayFBgn0039330 FlyAtlas2 - ADrosophilamelanogasterexpressionatlaswithRNA-Seq,miRNA-Seqandsex-specificdataFBgn0261575 Fly-FISH - AdatabaseofDrosophilaembryoandlarvaemRNAlocalizationpatternsCG11909 FlyMine - AnintegrateddatabaseforDrosophilagenomicsFBgn0261575 GenomeRNAi - Adatabaseforcell-basedandinvivoRNAiphenotypesandreagents43072 iBeetle-Base - RNAiphenotypesintheredflourbeetle(Triboliumcastaneum)TC008276 InterPro - Adatabaseofproteinfamilies,domainsandfunctionalsitesGlycosidehydrolasefamily31 Glycosylhydrolase,all-beta Glycosidehydrolasesuperfamily KEGGGenes - Molecularbuildingblocksoflifeinthegenomicspace.Dmel_CG11909 MARRVEL_MODEL - MARRVEL(modelorganismgene)43072 modMine - AdatawarehouseforthemodENCODEprojectFBgn0261575 LinkoutsDroID - Acomprehensivedatabaseofgeneandproteininteractions.FBgn0261575 DRSC - ResultsfrmRNAiscreensFBgn0261575 KEGGPathways - Wiringdiagramsofmolecularinteractions,reactionsandrelations.Galactosemetabolism Starchandsucrosemetabolism Metabolicpathways MIST(protein-protein) - AnintegratedMolecularInteractionDatabasetobi SynonymsandSecondaryIDs(6) ReportedAs SymbolSynonym CG11909(Zhangetal.,2019,Çiçeketal.,2016,Kemppainenetal.,2016,Bartoketal.,2015,Hosonoetal.,2015,Vartiainenetal.,2014,JapaneseNationalInstituteofGenetics,2012.5.21,EllisandCarney,2010,Nietal.,2010.12.1,Slacketal.,2010,Kelemanetal.,2009.8.5,Buchetal.,2008,Sturgilletal.,2007,Gronkeetal.,2005)CT33098(Cerianietal.,2002)Tobi(Delbareetal.,2020,Bostetal.,2018)tobi(Chowańskietal.,2021,SciambraandChtarbanova,2021,Wangetal.,2021,Zhouetal.,2021,Zhouetal.,2021,Hoodetal.,2020,Neamtuetal.,2020,Newelletal.,2020,Petal.,2020,Strilbytskaetal.,2020,Strilbytskaetal.,2020,Strilbytskaetal.,2020,Vásquez-Procopioetal.,2020,Huangetal.,2019,Moskalevetal.,2019,Valanneetal.,2019,Xuetal.,2019,Uedaetal.,2018,Ugrankaretal.,2018,Zhangetal.,2018,Gálikováetal.,2017,Kemppainenetal.,2016,Hentzeetal.,2015,Chatterjeeetal.,2014,EllisandCarney,2010,Buchetal.,2008,BuchandPankratz,2007) NameSynonyms targetofbraininsulin(Gaoetal.,2021,Buchetal.,2008,BuchandPankratz,2007)α-Glucosidase(Gronkeetal.,2005) SecondaryFlyBaseIDs FBgn0086730 FBgn0039330 Datasets(8) Studyfocus(0)ExperimentalRoleProjectProjectTypeTitleStudyresult(8)ResultResultTypeTitlescRNAseq_2020_Cattenoz_NI_seq_clusteringcellclusteringanalysis Clusteringanalysisofhemocytesfromnon-infestedthirdinstarlarvaescRNAseq_2020_Cattenoz_WI_seq_clusteringcellclusteringanalysis Clusteringanalysisofhemocytesfromwasp-infestedthirdinstarlarvaescRNAseq_2020_Cho_NI72LG_seq_clusteringcellclusteringanalysis Clusteringanalysisoflymphglandcellsfromnon-infestedlarvaeat72hafteregg-layingscRNAseq_2020_Cho_NI96LG_seq_clusteringcellclusteringanalysis Clusteringanalysisoflymphglandcellsfromnon-infestedlarvaeat96hafteregg-layingscRNAseq_2020_Cho_NI120LG_seq_clusteringcellclusteringanalysis Clusteringanalysisoflymphglandcellsfromnon-infestedlarvaeat120hafteregg-layingscRNAseq_2020_Cho_WI96LG_seq_clusteringcellclusteringanalysis Clusteringanalysisoflymphglandcellsfromwasp-infestedlarvaeat96hafteregg-layingscRNAseq_2020_Cho_NI96HL_seq_clusteringcellclusteringanalysis Clusteringanalysisofcirculatinghemocytesfromnon-infestedlarvaeat96hafteregg-layingscRNAseq_2020_Cho_NI120HL_seq_clusteringcellclusteringanalysis Clusteringanalysisofcirculatinghemocytesfromnon-infestedlarvaeat120hafteregg-layingReferences(65) ReportSections Open Close GeneralInformationGenomicLocationFunctionSummariesGeneModelandProductsExpressionDataAlleles,Insertions,Constructs,andAberrationsClassicalandInsertionAllelesTransgenicConstructsAberrations(DeficienciesandDuplications)Disease-ImplicatedVariantsPhenotypesOrthologsHumanOrthologsModelOrganismOrthologsOtherOrganismOrthologsParalogsHumanDiseaseAssociationsFunctionalComplementationInteractionsPhysicalInteractionreportGeneticinteractionsExternalDataPathwaysGenomicLocationandMappingStocksandReagentsOtherInformationCrossreferencesSynonymsandSecondaryIDsDatasetsReferences